Michael F. Salvatore, Ph.D

Michael F. Salvatore, Ph.D

Associate Professor

Department of Pharmacology, Toxicology, & Neuroscience

Molecular mechanisms of locomotor impairment associated with aging and Parkinson’s Disease.
  • Understanding the role of dopamine biosynthesis in locomotor capabilities
  • How loss of the dopamine phenotype, using in vivo Parkinson’s models, affects dopamine biosynthesis, reuptake, and locomotor activity and the impact of each on locomotor function or L-DOPA-induced dyskinesia
  • How glutamate reuptake dynamics affect nigrostriatal DA regulation and neuron viability in in vivo Parkinson’s models
  • How non-invasive behaviors of exercise and calorie restriction affect glutamate and dopamine regulation and reduce impact of aging on locomotor decline
msalva@lsuhsc.edu